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Ethics Compliance and Approval, Simplified

Cayuse IRB is an easy-to-use system for electronically preparing, submitting, and routing studies for IRB approval. It simplifies compliance with federal, state, and institutional governing bodies and helps ensure your human subjects research efforts conform to ethical guidelines. With increased transparency and productivity, studies can proceed smoothly through each step of the process, from creation to final approval.

Keep your data in the cloud for easy and secure access and collaboration anywhere

Get automated notifications for required tasks so nothing slips through the cracks


Configure templates and create intuitive drag-and-drop forms


Communicate more easily between committees, reviewers, and researchers


See faster turnaround times on exempt research and less administrative burden

Automatically report CITI® training to the IRB, thanks to seamless integration

IRB Common Rule Update

Compliance Date Revised to January 19, 2019.

For more information, please read our whitepaper: IRB Submission Software Makes Navigating New Changes, Like the Revised Common Rule, Easier.

Cayuse IRB - Protocols Management Software

Missouri State improves collaboration with Cayuse IRB.

Listen to Erin Parrish, Director of Research Administration, describe the direct and indirect benefits of collaboration while implementing and using Cayuse IRB on campus at Missouri State.

Role-Based Dashboards

Single-screen views of all phases of a protocol enable broad collaboration, increased user efficiency, and simplified institutional compliance. Role-based dashboards present protocol information, status, and tasks relative to your function, making it easier to find and complete your job at hand. Users performing multiple roles can easily switch between views to more efficiently identify what needs to be done for each role and each protocol.

Smart Forms for Intelligent Processing

Bring order and simplicity to the creation, modification, and completion of forms. Intuitive Smart Forms use an easy drag-and-drop builder to create and update forms, so you don’t need costly consultants or IT resources. Use conditional logic to build forms that dynamically skip or withhold questions depending on given answers — saving valuable processing time. Smart Forms can also be viewed and completed by multiple preparers in a secure environment, allowing for easy collaboration and a more streamlined process.

User Friendly

Backed by over two decades of satisfying the unique needs of research organizations, Cayuse IRB helps simplify complex compliance issues surrounding human subjects research. Cayuse IRB features an intuitive user-friendly interface that adapts to existing workflows to make the way you work easier and more productive. All Cayuse software solutions are built to enhance and advance society and include the best support services in the industry.

High-Performance Meetings

Automating workflows is great, but compliant, integrated workflows are even better! Cayuse IRB drives performance through meetings by integrating preparation and scheduling, agenda creation, attendance tracking, and meeting minutes into one solution. Agendas are automatically populated as protocols and added to meeting schedules. Protocol status is dynamically updated, capturing relevant tasks, action items, timelines, and responsible associates. All discussions and notes, including attendance, are easily captured as meeting minutes to simplify compliance.

Certified Time Savings

Designed with an AAHRPP accredited partner, workflows deliver maximum efficiency and ease-of-use. Principal investigators and staff can review, finalize, and submit protocols from anywhere with online submissions. Protocols reach your IRB office in real time, and electronic routing expedites the back and forth of the review and approval process. Automated notifications ensure protocols receive timely attention while comments and updates are timestamped to certify document integrity.

It’s Better in the Cloud

All the benefits of Cayuse IRB protocol automation are accessible anytime, anywhere through Cayuse’s cloud-based technology. Implementation times are lightning fast, and organizations eliminate infrastructure investments, disruptive upgrades, complicated customizations, and untimely backups. Processes and documents in the cloud deliver better data security, improved application uptime, and reduced impact on IT resources. The cloud also encourages collaboration, as the same familiar and easy-to-use workspace is accessible to all team members.

See why leading research organizations trust Cayuse to help them simplify their processes, mitigate compliance risk and increase collaboration.