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Protocols Management Software

Human Subjects Research Simplified.

Time to Transform your IRB Office

First of all, Cayuse IRB is built by research administrators, for research administrators. As a result, Cayuse IRB simplifies protocols management of your entire human subjects research portfolio, with best-practice workflows that improve productivity, mitigate risk and ensure compliance. A modern, user-friendly interface guides users through the complexities of protocol completion, submission, approval, and closure. Furthermore, automated routing with data transparency reduces IRB review and approval times, and easy, cloud-based access is guarded with ISO 27001 certified information security and data privacy.

IRB Common Rule Update

Compliance Date Revised to January 19, 2019.

The Federal delay will provide additional time for the necessary implementation of the 2019 requirements and for regulated entities to seek input from stakeholders through a notice and comment rulemaking process to allow for public engagement on the proposal.

For more information please read our whitepaper: IRB Submission Software makes navigating new changes, like the revised Common Rule easier.

Benchmarked Best Practices for Protocols

Ensure processes deliver maximum efficiency, compliance, and ease-of-use with workflows designed with an AAHRPP accredited partner

Flexible Smart Forms

Easily create, update and modify complex questionnaires and forms with a simple drag-and-drop designer

Integration with CITI©

Automatically report completed training to the Collaborative Institutional Training Initiative (CITI) Program. Monitor training credentials and keep track of progress with Cayuse electronic IRB.


ISO 27001 Certified

Experience secure anytime, anywhere access from the only Electronic Research Administration provider with ISO 27001 vendor certification – so you know your data is always safe!

Cayuse IRB - Protocols Management Software

Missouri State improves collaboration with Cayuse IRB.

Listen to Erin Parrish, Director of Research Administration describe both the direct and indirect benefits of collaboration while implementing and using Cayuse IRB on campus at Missouri State.

Smart Forms for Intelligent Processing

Bring order and simplicity to the creation, modification, and completion of forms. Intuitive Smart Forms use an easy drag-and-drop builder to create and update forms, so you don’t need costly consultants or IT resources. Use conditional logic to build forms that dynamically skip or withhold questions, depending on given answers—saving valuable processing time. Smart Forms also can be viewed and completed by multiple preparers in a secure environment, allowing for easy collaboration and a more streamlined process.

Role-based Dashboards

Single-screen views of all phases of a protocol enable broad collaboration, increased user efficiency and simplified institutional compliance. Role-based dashboards present protocol information, status and tasks relative to your function, making it easier to find and complete your job at hand. Users performing multiple roles can easily switch between views to more efficiently identify what needs to be done for each role and each protocol.

Certified Time Savings

Designed with an AAHRPP accredited partner, workflows deliver maximum efficiency and ease-of-use. Principal investigators and staff can review, finalize, and submit protocols from anywhere with online submissions. Protocols reach your IRB office in real time, and electronic routing expedites the back and forth of the review and approval process. Automated notifications ensure protocols receive timely attention, while comments and updates are timestamped to certify document integrity.

High-Performance Meetings

Automating workflows is great, but compliant, integrated workflows are even better! Cayuse IRB drives performance through meetings by integrating preparation and scheduling, agenda creation, attendance tracking and meeting minutes into one solution. Agendas are automatically populated as protocols are added to meeting schedules. Protocol status is dynamically updated, capturing relevant tasks, action items, timelines and responsible associates. All discussions and notes, including attendance, are easily captured as meeting minutes to simplify compliance.

It’s Better in the Cloud

All the benefits of Cayuse IRB protocol automation are accessible anytime, anywhere through Cayuse’s cloud-based technology. Implementation times are lightning fast, and organizations eliminate infrastructure investments, disruptive upgrades, complicated customizations, and untimely backups. Processes and documents in the cloud deliver better data security, improved application uptime, and reduced impact on IT resources. The cloud also encourages collaboration, as the same, familiar, easy-to-use workspace is accessible to all team members.


Backed by over two decades of satisfying the unique needs of research organizations, Cayuse IRB helps simplify complex compliance issues surrounding human subjects research. Cayuse IRB features an intuitive user-friendly interface that adapts to existing workflows to make the way you work easier and more productive. All Cayuse software solutions are built to enhance and advance society and include the best support services in the industry.