Cayuse connects people, processes, and data across the research lifecycle, helping organizations streamline administration, improve visibility, reduce risk, and support better research outcomes.
Electronic Research Administration (eRA) Software
Connect the full research lifecycle in one cloud-based suite
$45.3B
In federal funding proposals processed in 2025
67%
Average reduction in review times
99.9%
First-time submission success rate
Trusted by organizations just like yours
Administrative software built for the way research works
Pre-award Research Management
Get funded faster
Support the pre-award process from funding discovery through proposal submission. Cayuse helps research teams identify relevant award opportunities, develop proposals, coordinate routing, and move submissions through institutional review more efficiently for a 99.9% first-time submission success rate.
Post-award Research Management
Maintain visibility throughout the award lifecycle
Manage awards, agreements, effort reporting, budgets, and financial activity in a connected ecosystem. Cayuse gives research administrators, finance teams, and investigators greater visibility into award requirements and financial status so they can stay ahead of reporting, compliance, and closeout responsibilities.
Sponsored Projects | Fund Manager | Project Effort | Agreements
Compliance Management
Keep complex research operations secure and compliant
Simplify compliance oversight for human subjects research, animal research, biosafety, and conflicts of interest. Cayuse helps research organizations simplify IRB, IACUC, IBC, and COI protocols and disclosures, standardize reviews, maintain documentation, track approvals, and give administrators greater visibility across compliance activities.
Enterprise Risk & Compliance | Human Ethics | Animal Oversight | Outside Interests | Hazard Safety
Vivarium Management
Modernize vivarium facility management
Organize animal facility operations, vet care, and scheduling within a structured environment. Cayuse helps vivarium teams streamline animal ordering, census scanning, and invoicing, ensure accurate veterinary medical records, and coordinate hubandry personnel and task scheduling, all with real-time data visibility to ensure consistent progress.
Technology Transfer Software
Bring discoveries to the market faster
Oversee the full technology transfer process with one software solution. Cayuse helps research teams own research commercialization with tools for easy applications, patent monitoring, invention disclosure form capture, and marketing, while one-click iEdison and AUTM reporting ensures all work maintains compliance and standardized documentation.
Data Management
Make data driven decisions
Connect and leverage your data to ensure compliance, empower decision-making, and simplify reporting. Cayuse enables organizations to view, extract, analyze, and share data from their applications to keep records accurate, stakeholders aligned, and growth initiatives on track.
Connected by design
Unite information, workflows, and teams across the research lifecycle
Eliminate silos
Easily share data, project statuses, submissions and updates with stakeholders, teams, and departments across your organization within Cayuse’s secure applications.
Improve visibility
Role-based dashboards and app transparency give researchers, administrators, reviewers, and other stakeholders fast access to up-to-date project information from their devices.
Reduce risk
Maintain compliance with federal agencies and regulations via easy disclosures, simplified protocol submissions, and automated notifications for deadlines and red flags.
Scale with your needs
Cayuse is designed with growth in mind, with configurable workflows that can adapt to the changing needs of your organization, no matter the size.
Make impactful decisions
Harness real-time, actionable insights to inform resource allocation, effectively plan for the future, and make data driven decisions.
Improve collaboration
User-friendly interfaces and easy-to-use workflows encourage researchers and administrators to work together to keep projects on track.
The Cayuse Difference
Cayuse is purpose-built for organizations managing complex research programs with tools to manage funding, administration, compliance, and operations. Institutions can reduce fragmentation, improve visibility, and support research teams across the full lifecycle with Cayuse’s connected suite of solutions.
The #1 research administration tool for organizations of all sizes
From growing research programs to large universities, academic medical centers, healthcare organizations, and enterprise research institutions, we support complex organizational structures, both low- and high-volume workflows, and institution-specific processes.
Secure infrastructure, encrypted data transmission, and best-in-class availability
At Cayuse, we help institutions around the world manage billions of dollars worth of research, funding, and data. Our reliable cloud storage is powered by AWS, audited to SSAE 16, SOC 2, and PCIA standards, and ISO 27001 certified to keep that data safe. Secure network architecture ensures access is limited to authorized personnel and services.
The most experienced team
Cayuse combines purpose-built software with research, implementation, and support expertise. From answering questions to providing technical assistance, you’ll work with Cayuse team members who come from research and grant administration backgrounds across major industries. We understand the compliance challenges research organziations manage every day because we’ve been in your shoes.
“When our CEO and top leadership saw the analytics, they loved it. We’re so thrilled to have a powerful tool that’s so easy to use!”
“Putting a prepared budget into an R&R budget form used to take twice as long as it does now with Cayuse Proposals (S2S).”
“If you have a problem that your current solution is not meeting, I would consider talking with Cayuse and seeing if they can help you. Chances are they can because of the malleability of the system.”
"All the options Cayuse gave us have taken away extra outside PDFs and emails; we’re taking everything from outside of the system and getting one clear picture… Everything’s in one place, not everywhere."
Our Services
A proven and trusted partner for transforming research administration
We’re here to support your journey, whether you’re just starting out or well-established and continuing to grow. Our team of implementation, services, and support professionals strives to ensure you have a dependable advocate in every interaction. With Cayuse, you’ll join a built-in community eager to connect, learn, and grow alongside your team.
Implementation Services
We’re committed to setting you up for success from day one. Cayuse leads the market in completed implementations. Our proven planning process ensures consistent results with efficient time-to-value. In-house experts will guide you every step of the way, working in close collaboration to understand your requirements, migrate data, and ensure a successful launch.
94%
Customer satisfaction rate
Managed Services
Boost capacity and productivity with Cayuse on your team. No two organizations are alike, and we know that customers have unique needs when it comes to implementation, training, and continued support. Our Managed Services can be tailored to fit your goals and maximize your resources for key initiatives.
Get in touch
See the Research Suite in action
Discover how Cayuse can connect every stage of research administration at your organization.
Powering smarter research workflows
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Research Suite FAQs
Frequently Asked Questions
The Cayuse Research Suite is a collection of cloud-based research administration software supporting the full research lifecycle, including applications for managing pre-award, post-award, compliance, vivariums, and technology transfer.
The Research Suite is designed to facilitate centralized task management with unified user data and select integrations between Cayuse applications, institutional enterprise software such as ERP, HR, financial, and payroll systems, and the global research ecosystem including Grants.gov, the NIH, CITI, and more.
Cayuse’s Award Management solutions for pre-award workflows reduce the administrative burden typically involved in the search for funding and collaborators, proposal development, and proposal submissions.
Cayuse Fund Finder improves the funding search with a single point of entry for browsing and searching for funding opportunities from a wide range of grantees, both private and federal. Automated alerts notify users of new and active funding opportunities, while grant recommendations tailor potential funding sources to the specifics of your projects.
Cayuse Proposals (S2S) eliminates redundant data entry with repeatable workflows and autofill capabilities, ensuring accuracy for first-time federal submissions, and reducing rework or last-minute errors. The software’s single submission portal for 30+ agencies simplifies routing, approvals, and training, helping users achieve a 99.9% first time successful submission rate and 30% faster completion times compared to using agency portals.
Cayuse Sponsored Projects provides easy proposal initiation with one button to start a new proposal and the ability to add multiple users in a collaborative workspace, helping to improve submission accuracy. Automated proposal routing also saves hours per proposal and accelerates the time-to-award.
Cayuse’s Award Management solutions for post-award workflows reduce the administrative burden typically involved in award setup and management, budget oversight, agreements management, effort certification, reporting, and project closeout.
In addition to simplifying the pre-award stage of a project’s lifecycle, Cayuse Sponsored Projects centralizes and automates pre-award processes including approvals and closeout, helping users process more awards per FTE, achieve cleaner audits, and deliver faster turnarounds for PIs and sponsors. Sponsored Projects’ centralized proposal and award records cut manual tracking times in half, while standardized data collection and transparent user dashboards provide easy access to real-time project updates and improve audit prep efficiency by 50%.
Cayuse Fund Manager gives researchers and finance teams real-time visibility into grant spend and projections, enabling spend-to-zero performance on 75% of awards. With grant-friendly language developed with research teams in mind, institutions can reallocate 0.5-1 FTE per $50M in research spend by freeing grant/central accountants and finance teams from ad-hoc data pulls.
Cayuse Project Effort automates federal effort certification and payroll verification, reducing audit exposure and freeing hundreds of administrative hours annually. The software’s automated effort sheets take minutes instead of hours and feature one-click approval from desktop or mobile devices and digital routing and approval cuts certification cycle time by 70%. Institutions typically reclaim 0.5–1 FTE by replacing manual spreadsheets and signatures with automated routing and validation.
Cayuse Agreements centralizes the intake, negotiation, routing, and execution of all research-related agreements, including sponsored, non-sponsored, clinical trial, data-use, and material-transfer. Smart form templates standardize intake and data capture for every agreement type, while Agreements’ central repository for executed documents enables instant search and audit access. Institutions using Agreements experience faster turnaround times, significant risk reduction, and measurable staff time savings by eliminating manual email and spreadsheet tracking.
Cayuse’s Compliance Management solutions deliver a unified, enterprise compliance ecosystem that connects people, protocols, and projects, with measurable ROI in time savings, compliance accuracy, and research throughput.
Cayuse IRB streamlines the human subjects research approval process, helping institutions reduce IRB turnaround times by 30-50%, improve compliance accuracy, and provide transparent visibility for researchers and reviewers. The software’s smart forms guide users through complex IRB logic for fewer resubmissions, while transparent review histories provide clarity and accountability. Institutions can shorten approval cycles and accelerate research starts with automated submissions, reviews, and approvals, and built-in routing, alerts, and reporting.
Cayuse IACUC automates the full animal use protocol lifecycle, reducing review and approval time by 35-45% and improving transparency for all stakeholders. Cayuse IACUC’s configurable smart forms and procedural libraries cut prep time by 30%, while automated routing and digital sign-off to save 10+ hours per protocol.
Cayuse IBC automates biosafety protocol management, enabling faster reviews, consistent documentation, and improved regulatory compliance. Guided smart forms tailored to research type reduce protocol prep time by 35%, and built-in meeting management and reporting tools streamline documentation for regulators. Institutions using Cayuse IBC report 30–40% faster approvals and significant reductions in incomplete or inaccurate submissions compared to manual processes.
Cayuse COI simplifies and automates conflict-of-interest disclosures and provides built-in management plan creation, reducing administrative workloads by up to 60% and ensuring compliance with federal and institutional regulations. COI’s easy, online disclosure process and automated reminders cut manual follow-ups by 70%, while the software also allows stakeholders to amend disclosures mid-cycle without re-entering pre-disclosed conflicts. Cayuse COI helps institutions achieve higher completion rates and simplifies management of conflicts or financial interests.
Cayuse’s Vivarium Management solutions enable animal research teams to easily track censuses, automate billing, schedule staff and veterinary care, and stay ahead of compliance requirements, all in one secure, cloud-based system.
Cayuse Vivarium Operations unifies animal procurement, census, service charges, and billing processes, cutting facility management workload by 30-50%. The software’s real-time mobile census and procurement tracking reduces manual updates and decreases incorrect per-diems by 60%, while streamlined billing with error-free reconciliation leads to fewer invoice disputes and missed charges. Vivarium Operations’ automation enables full cost recovery and transparency across PI invoices, improving billing accuracy and revenue capture.
Paired with Vivarium Operations, Cayuse Vet Care automates animal health recordkeeping and clinical workflows, reducing documentation time by 40% and improving intervention response time by up to 60%. The software’s real-time health reporting and treatment documentation reduces paperwork by hours and increases confidence in compliance.
Cayuse Schedules manages animal husbandry scheduling and activity tracking, eliminating manual checklists and improving task completion visibility by 80-90%. Schedules’ task reassignment addresses call-outs and ensures critical husbandry activities are properly allocated, with metric-based workload allocation and full visibility into daily facility operations and compliance status.
Cayuse Inventions consolidates disclosure, patent, and licensing workflows, helping tech transfer offices manage IP portfolios 30-40% more efficiently and increasing commercialization throughput by 20-25%. End-to-end IP tracking, marketing, and licensing workflows give institutions full control of their commercialization efforts, and standardized AUTM and iEdison reporting, integration with CPI annuity management service, and easy invention disclosure and agreement request features help bring research breakthroughs to the market faster.
The Cayuse Platform and integrations between software solutions help connect records, facilitate the movement of information between research processes, centralize research data, and enable easier reporting and data-driven decision making.
Cayuse Report Connector provides access to data across the Cayuse Research Suite, allowing institutions to analyze proposal activity, award management, post-award administration, compliance, and other research administration functions using their preferred reporting tools, such as Microsoft Power BI or SQL Server Reporting Services (SSRS).
Specific integrations include, but are not limited to:
- Sponsored Projects integrates with Fund Manager, IRB, IBC, and COI to enable end-to-end portfolio visibility, reducing reconciliation effort by 50% and strengthening institutional compliance posture.
- Proposals (S2S) integrates with Sponsored Projects to help institutions eliminate duplicate entry of 16 core data fields and maintain 100% congruency between proposal intent and award data, reducing audit risk and manual reconciliation.
- Fund Finder integrates with Proposals (S2S) and Sponsored Projects to provide a seamless pipeline from opportunity identification to proposal submission, reducing administrative burden and helping institutions convert more opportunities into awards.
- Fund Manager integrates with Sponsored Projects to display spend-down data within the Sponsored Projects solution, creating a single entry point for both pre- and post-award teams and saving hours per reporting cycle.
- Project Effort integrates with institutional payroll and HR systems, enabling institutions to eliminate duplicate effort certification steps and improve accuracy across all research cost centers.
- Agreements integrates with Sponsored Projects to link executed agreements to corresponding proposals and awards for complete lifecycle traceability, and centralize visibility across contracts, awards, and subawards for stronger compliance oversight and revenue forecasting.
- Insights is natively integrated with Sponsored Projects, helping institutions leverage their Cayuse data to identify bottlenecks and performance gaps, increase research ROI, and reduce reporting labor costs with less manual data aggregation and duplication across systems.
- IRB, IBC, and COI integrate with Sponsored Projects to ensure congruency between funded projects, human subjects protocols, biosafety protocols, and disclosures.
- IACUC integrates with IBC for cross-committee validation of approvals and with Vivarium Operations to track animal usage and ensure animal requisitions and breeding activities are aligned with IACUC approvals.
- Vivarium Operations integrates with Vet Care for synchronized animal tracking and health reporting, ensuring congruency across research, animal care, and finance.
- Schedules integrates with Vivarium Operations to leverage census data for workload distribution, reducing under- or over-allocation of care staff time by 20-25%.
- Inventions integrates with Sponsored Projects for complete visibility from funded research through commercialization, closing the loop on research impact.
Yes, the Cayuse Research Suite integrates with existing institutional systems including ERP, finance, HR, payroll, and more to coordinate project and personnel data and reduce duplicate data entry. Cayuse customers may opt for additional Managed Services to ensure consistent, reliable data exchanges across Cayuse and connected systems as external processes and institutional needs change.
Yes, Cayuse’s solutions can be implemented individually to meet organizational needs, leaving room for expansion as institutional priorities evolve. Cayuse ensures institutions get up and running faster with individually mapped implementation plans tailored to different needs and resources.
Cayuse breaks implementations down into five steps:
- Discovery: From kickoff to discovery sessions, we’ll analyze your requirements and restrictions to fully map an optimal implementation process.
- Configuration: We’ll set up your new software to meet your needs by establishing workflows, loading legacy data, building automation rules, and more.
- Validation: Our team performs thorough testing before rollout, with validations for both critical business processes and edge cases to make sure nothing falls through the cracks.
- Enablement: Cayuse facilitates enablement sessions and delivers training resources to make sure you’re ready to unveil and use your new solutions.
- Deployment: Your new software will go live following a pre-defined deployment strategy.
Following implementation, Cayuse provides ongoing support to ensure continued success and product satisfaction. Additional Managed Services are also available to help customers maintain ongoing alignment between their software and institution, reduce internal workloads with dedicated specialists, improve data organization and integrations, and increase buy-in and user confidence.
Cayuse is suitable for all organizations that conduct research and manage grants. Our customers include R1 and R2 research institutions, research colleges and universities of all sizes, HBCUs, community college systems, healthcare research organizations, academic medical centers, life sciences companies, nonprofits, government organizations, and international institutions.